Tuesday, October 8, 2019

The Pap Smear Test For Cervical Cancer Research Paper

The Pap Smear Test For Cervical Cancer - Research Paper Example The article also has data on prevalence and epidemiology of cervical cancer and recommends regular screening. The accuracy of the test is influenced by a number of factors; typically determination of both sensitivity and specificity for a test involves studies applying standard testing on all the participating persons. Studies comparing the test have shown its detection sensitivity to be between 55% - 80% but due to the slow pace at which cervical cancer grows; sensitivity can be higher in a program of regular screening with Pap. In determining the test’s sensitivity and specificity, there is the requirement for defining a standard for the test as well as the standard threshold for reference. ASCUS is mostly applied as the threshold for the test while CIN 1 is utilized as the standard for reference. With the combination, the sensitivity of approximately 68% is achieved and 75% specificity. LSIL could be the most appropriate threshold for the test when used with CIN 2-3 as the standard for reference and with this combination, up to 70%-80%, sensitivity & 95% specificity levels are achieved. It is important to note that obtaining adequate specimen is crucial in determining accuracy and integrity of a Pap smear test. In conclusion, therefore, screening is very important in the management of cervical cancer and therefore regular testing is recommended for women. Sensitivity and specificity of the test can be very high if the screening is done appropriately with the adequate specimen and large cohorts of participants.

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